The side effects of Masteron Enanthate can and primarily surround those of an androgenic nature. The androgenic side effects of Masteron Enanthate may include acne, hair loss in men predisposed to male pattern baldness and body hair growth. Despite a potent binding relationship to the androgen receptor the total androgenic activity should not be extreme and such side effects should not be extreme. If you are predisposed to male pattern baldness this steroid is well known for speeding up hair loss and should be avoided if that is a concern. If you are not predisposed hair loss is impossible.
Important Note: the 5-alpha reductase enzyme, the enzyme that reduces testosterone to DHT, does not metabolize Drostanolone. There is no reduction; it’s already DHT. Because no reduction exists there is nothing to inhibit or block and this means 5-alpha reductase inhibitors like Finasteride will do nothing to combat androgenic effects.
Masteron Enanthate can also promote virilization symptoms in women. Virilization refers to the promotion of male characteristics in women, specifically body hair growth, a deepening of the vocal chords and clitoral enlargement. It is very possible to use this steroid without these issues, although genetic sensitivity will play a role. If symptoms begin to show simply discontinue use and they will rapidly go away. It is when virilization symptoms are allowed to set in that they become a problem and in some cases irreversible.
Important note: Female users of Drostanolone will be best served by choosing Drostanolone Propionate as it will clear the body faster should issues arise.
Estrogen, which is the main enemy of breast cancer patients, is curbed through SERM and AI. Master also shares these characteristics and is capable of preventing estrogen buildup in the body. As DHT derivative, it does not allow aromatization and displays strong anti-aromatase properties. For this reason, Masteron has been used in combination with other drugs to treat breast cancer patients. The role of Masteron then was to block the amount of estrogens in the body while other drugs, such as Tamoxifen-citrate were used to block the binding of estrogen at the breast receptors. Today, many other more powerful aromatase inhibitors have replaced this breast cancer treatment to achieve even greater success in the fight against breast cancer.
As a bulking agent, the effects of Masteron will prove to be rather weak. It is possible the hormone could provide gains in mass similar to Primobolan (which wouldn't be that strong either) if the total dose was sufficiently high. However, the relative gain in size will be moderate with many anabolic steroids being far more suited for this period of steroidal supplementation. Masteron does not aromatize and is not estrogenic; in fact, it shows anti-estrogenic traits in the body and binds to aromatase instead of other substrates. This is why it has been effective in the treatment of breast cancer.