Glucocorticoids are a class of corticosteroids that affect the metabolism of carbohydrates , fat , and proteins , and regulate glycogen and blood pressure possess pronounced anti-inflammatory activity and cause alteration of connective tissue in response to injuries. The anti-inflammatory and connective tissue effects of glucocorticoids might mask injuries, leading to more serious injuries to athletes. Because of this and metabolic regulation effects, the administration of any glucorticoid orally, rectally, intraveniously, or intramuscularly is prohibited and requires a therapeutic use exemption. Topical uses of glucocorticoids does not require an exemption.
The mean oral bioavailability of finasteride is approximately 65%.  Its volume of distribution is 76 L/kg.  The plasma protein binding of finasteride is 90%.  The drug has been found to cross the blood–brain barrier , whereas levels in semen were found to be undetectable.  Finasteride is extensively metabolized in the liver , first by hydroxylation via CYP3A4 and then by aldehyde dehydrogenase .  The metabolites of finasteride have about 20% of its potency in inhibiting 5α-reductase and hence its metabolites are not particularly active.  The drug has a terminal half-life of 5 to 6 hours in adult men (18–60 years of age) and a terminal half-life of 8 hours or more in elderly men (greater than 70 years of age).  It is eliminated as its metabolites 57% in the feces and 40% in the urine .